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Rochester, MN
Describes the nature of a clinical study. Types include:
The purpose of this study is to develop and pilot test a culturally relevant, Facebook delivered intervention to promote smoking treatment uptake and cessation among Alaska Native (AN) smokers.
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Eau Claire, WI
The purposes of this study are to determine the relationship between the use of e-cigarette and perceived social support in young adults, to characterize the pattern of co-use of nicotine and cannabis e-cigarette in young adults, and to identify if co-use of nicotine and cannabis e-cigarettes is a risk factor for use of combustible forms of tobacco and cannabis.
This present effort is the first step of a larger study. We are limiting the scope this AAIRB application to only the first step. The goal of the overall research study is to examine the acceptability and feasibility of using NMR to inform selection of pharmacologic treatment to increase smoking abstinence among ANAI people.
The aim of this IRB application (Aim 1a) is to refine a metabolism-informed pharmacologic intervention to optimize design and participation of a future pilot.
We will use a community-based participatory research (CBPR) approach with ANAI customer-owners, providers, and leaders to refine intervention materials and protocols used by Wells et al. for use in an ANAI clinical environment. By eliciting feedback on the acceptability and feasibility of components of the intervention through interviews, we will be able to refine the design of the intervention and future pilot.
Then, in a future AAIRB application, we will use rapid-cycle methods to beta-test the intervention with 10 customer-owners to further optimize the intervention (Aim 1b). In a third and final AAIRB application pertaining to this study, we will assess the refined intervention in a single-arm pilot (Aim 2). The current IRB application (Aim 1a) is only to conduct interviews to refine an NMR intervention and pilot design.