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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study to Evaluate the Safety of ART352-L in Subjects Undergoing Posterolateral Spinal Fusion

    Rochester, MN

  2. Transforaminal Lumbar Interbody Fusion (TLIF)

    Scottsdale/Phoenix, AZ

  3. A Study to Evaluate Awake vs. Asleep Spine Surgery

    Jacksonville, FL

  4. A Study to Assess Wound Closure Techniques in Primary Spine Surgery Using SPY Intra-operative Angiography

    Rochester, MN

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