Infectious Diseases Research

Below are current clinical trials.

203 studies in Infectious Diseases Research
(all studies, either open or closed).

Filter this list of studies by location, status and more.

1. A Study to Evaluate Clazakizumab in Patients with Life-threatening COVID-19 Infection (Enrolling by Invitation Only)

   Scottsdale/Phoenix, Ariz.

   The primary purpose of this study is to assess the safety of clazakizumab treatment in COVID-19 infected patients with respiratory failure due to hyperinflammation related to cytokine storm.

2. A Study to Evaluate Near-Patient Tests for the Direct Detection of SARS-CoV-2

   Scottsdale/Phoenix, Ariz.

   The pupose of this study is to evaluate near-patient methods, including both point of care (POC) and patient-performed testing.

3. Long-term Effects of SARS-CoV-2

   Jacksonville, Fla.

   The purpose of this study is to perform an ambi-directional clinical, neurological, cognitive, functional, and blood boimarker study of hospitalized patients with and without COVID-19.

    

    

    

4. Home Screening for COVID-19

   Rochester, Minn.

   An important means to control the COVID-19 pandemic is the rapid identification of infected individuals to allow quarantine and therapy to be promptly delivered.  At home testing will soon be available, but requires reagents and introduces a delay.  The possibility of combining a limited number of Mid-Turbinate (MT) nasal swab tests, Dried Blood Spot (DBS) serology, and smartphone-enabled electrocardiogram (ECG) tests may permit daily rapid, under one minute tests potentially, if this method proves to be effective. We plan to enroll 900 participants to determine if we can detect conversion in all modalities.

5. Analysis of Blood and Urine for Microbial Pathogen Discovery and Undiagnosed Infection

   Rochester, Minn.

   The aim of this study is to identify difficult to diagnose microbial pathogens causing infections using blood or urine for identification of bacteria, viruses, fungi or parasites that are not detectable or are difficult to detect using current diagnostic techniques.

6. Voice Signal PASC Study

   Rochester, Minn.

   The purpose of this study is to remotely use the Ellipsis Health (EH) voice analysis technology to record the speech patterns and content of individuals with a recent diagnosis of Coronavirus-19 (COVID-19) presenting to the post-COVID-19 clinic at Mayo Clinic, to validate its use as a tool to screen for major depressive disorder (MDD) and generalized anxiety disorder (GAD) against gold-standard questionnaires used in clinical practice namely the PHQ-9 and GAD-7

7. A Study to Assess the Burden of Respiratory Syncytial Virus Infections in Older Adults in a North American Community

   Rochester, Minn.

   The primary purpose of this study is to estimate the incidence rate of confirmed respiratory syncytial virus (RSV) (and other confirmed respiratory viruses) infections and associated adverse outcomes.

8. A Study to Collect Tissue, Fluids, Blood and/or Fungal Samples in Patients with Pulmonary and Extrapulmonary Coccidioidomycosis

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to create a biorepository of tissue, fluid and fungal specimens for future studies.

9. SER-109 Versus Placebo To Prevent Recurrent Clostridium Difficile Infection (RCDI)

   Rochester, Minn.

   The study will involve administering the study drug as a single dose of study drug or placebo. This study is designed to demonstrate the superiority of the experimental drug versus placebo in adult patients with recurrent CDI.

10. A Study to Evaluate the Immune Response of Healthy Individuals for the 2017-2018 Seasonal Flu Vaccine

    Rochester, Minn.

    The purpose of this study is to evaluate the immune response of healthy individuals to the 2017-2018 seasonal flu vaccine.