Daryl J. Kor, M.D.

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SUMMARY

The clinical research laboratory of Daryl J. Kor, M.D. focuses on topics related to blood health during a surgical hospital stay and blood management. To facilitate this research agenda, Dr. Kor has explored and become experienced with the use of novel data and biomedical informatics solutions in support of clinical research. Much of his prior work focused on the use of innovative informatics approaches to improve the understanding of the role of hospital events and associated patient responses on the development of perioperative complications.

Focus areas

• Transfusion therapy. Dr. Kor's primary research focus relates to perioperative blood health and patient blood management. He is specifically interested in improving the understanding of transfusion efficacy and risks associated with blood product administration. He has a particular interest in the epidemiology of transfusion-related pulmonary complications, the impact of red blood cell storage duration, and the risks and benefits of prophylactic transfusion therapies.
• Epidemiology, pathophysiology and treatment of postoperative organ issues. Dr. Kor's work in this space has specifically focused on acute respiratory distress syndrome and acute kidney injury. As effective treatment strategies are lacking for these serious postoperative complications, his work is dedicated to their prevention. These efforts are centered on two key aims that involve identifying:
  • People who are at high risk by using advanced modeling techniques.
  • Intermediate markers that can accurately and reliably predict the development of the fully established syndromes.

Significance to patient care

Dr. Kor's research leads to improved identification of patients who are likely to experience either harm or benefit with transfusion therapies. His work also leads to a better understanding of potential prevention strategies for postoperative complications. Dr. Kor's lab takes advantage of medical informatics and electronic health records to facilitate knowledge discovery and implementation of best practices. These efforts improve quality of care in the perioperative environment with particular emphasis on the intensive care unit.

Professional highlights

• Co-lead, Biomedical Informatics Program, Center for Clinical and Translational Science, Mayo Clinic, 2023-present.
• Dean of Research Data and Digital Solutions, Mayo Clinic, 2023-2024.