Location

Rochester, Minnesota

SUMMARY

Jay Mandrekar, Ph.D., is the primary statistician for Mayo Clinic's Department of Neurology, Department of Surgery, and the Divisions of Infectious Diseases and Clinical Microbiology. He is involved in multiple clinical trials, population-based studies and research grants in these areas. Dr. Mandrekar also has grants in nursing research and vascular and interventional radiology.

Dr. Mandrekar's primary research interest is in the application and extension of statistical methods for the evaluation of the quality and domains of various entities. The areas he studies and evaluates are clinical teaching, multiple sclerosis and other neurological diseases, prosthetic joint infections, and assays for viral detection.

Focus areas

  • Factor analysis and hierarchical cluster analysis
  • Generalized estimating equations
  • Regression methods and interrater reliability
  • Macros for statistical procedures
  • Large scale data analysis

Significance to patient care

The application of appropriate — and sometimes sophisticated — statistical approaches to data from well-conducted clinical trials, laboratory experiments and database studies have produced practice-changing results. These results include the implementation of viral detection assays and improved clinical management of people with neurological and infectious diseases at Mayo Clinic and worldwide.

The application of factor analysis and principal components analysis, allowing for correlated data, has helped to further the understanding of the underlying factor structure in questionnaires. These questionnaires are administered to assess, for example, resident doctors' reflections on quality improvement.

Professional highlights

  • Member, biostatistical editorial board, Mayo Clinic proceedings, 2013-present.
  • Core director, biostatistics, Mayo Clinic, 2014-2021.
  • Biostatistics editor, Cephalalgia, 2008-2017.
  • Standing member, Cancer Immunopathology and Immunotherapy Study Section, National Cancer Institute, 2008-2013.
  • Co-director, biostatistics workshop, 15th Congress of the International Headache Society, 2011.
  • Co-director, biostatistics workshop, World Federation of Neurology Headache Research Group, 2010.

PROFESSIONAL DETAILS

Primary Appointment

  1. Consultant, Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences

Joint Appointment

  1. Consultant, Department of Neurology
  2. Consultant, Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology

Academic Rank

  1. Professor of Biostatistics
  2. Professor of Neurology

EDUCATION

  1. PhD - Biostatistics Ohio State University
  2. MS - Statistics Ohio State University
  3. MS - Biostatistics University of Michigan
  4. MSc - Statistics University of Bombay
  5. BSc - Statistics University of Bombay
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BIO-00027572

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