Genetics of Alzheimer's Disease and Endophenotypes: Nilufer Ertekin-Taner

Presentations

Genetics of gene expression in Alzheimer's disease and progressive supranuclear palsy

• Transcript profiling analysis of Alzheimer's disease brains (PPT)
• Investigation of established AD risk SNPs for association with AD in an African American case-control series (PPT)
• Novel late-onset Alzheimer's disease loci variants associate with brain gene expression (PPT)
• Association of glyceraldehyde-3-phosphate dehydrogenase locus variant with late-onset Alzheimer's disease (PDF)
• Investigating cis-SNP/mRNA level associations of candidate Alzheimer's disease genes in different brain regions of patients and controls (PDF)
• MAPT haplotypes associate with Alzheimer's disease risk and brain gene expression (PPT)

Mapping and functional characterization of novel Alzheimer's disease risk genes and alleles

• LRRTM3 interacts with APP and BACE1, influences APP processing and has variants associating with late-onset Alzheimer's disease (LOAD) (PPT)
• Association study of late-onset Alzheimer's disease risk variants and risk for posterior cortical atrophy (PPT)
• Association study of late-onset Alzheimer's disease risk variants and memory decline (PPT)
• Association of candidate gene susceptibility alleles on chromosome 10 with AD risk and endophenotypes (PDF)
• Association of common KIBRA variants with episodic memory and AD risk (PDF)