Overview

Under the direction of principal investigator Matthew J. Maurer, M.S., D.M.Sc., the Lymphoma Biostatistics and Data Science Laboratory at Mayo Clinic uses analytical methods to advance scientific understanding about causes, treatments and outcomes for cancers of the lymphatic system and bone marrow.

In particular, our lab focuses its research efforts on these cancers:

• Hodgkin lymphoma (Hodgkin's disease)
• Non-Hodgkin's lymphoma

Although researchers have made progress in understanding what causes these cancers and how to treat them, there is still much to learn about prevention, diagnosis, treatment and survivorship.

One of our lab's major research goals is to improve outcomes for patients with lymphoma by utilizing observational and clinical trial data. Areas of focus include:

• Developing risk models, nomograms, and electronic applications to aid clinicians and patients in risk assessment and prognosis.
• Identifying and evaluating of novel clinical endpoints for disease outcomes.
• Improving how we design clinical trials and evaluate their results.

Another major goal is to provide expertise in data management for studies that identify lifestyle, genetic, tumor, clinical, and treatment factors that are associated with better cancer outcomes and survivorship among patients with lymphoma. Our lab serves as the data center for several large multicenter studies of lymphoma, including the Lymphoma Epidemiology of Outcomes Cohort Study and the International FLIPI24 Consortium. In addition, we provide guidance in the utilization and analysis of these (and other) data resources to researchers at Mayo Clinic and around the world.