Clinical Trials

The purpose of this study is to update our online decision aid for the treatment of osteoporosis to incorporate new treatment options and to prototype and field test the updated decision aid within the Bone Clinic (Endocrinology) and primary care clinics at Mayo Clinic.

The purpose of this study is to assess fall risks as measured by gait and postural parameters obtained by smart sensor with osteoporotic fallers comparing individuals:

1. With fracture vs. no fracture
2. upper extremity vs. lower extremity fracture
3. Non-hip vs. hip fracture

The Photon Counting Detector Computed Tomography (PCD-CT) Spectral Topogram can be resolved into multispectral components given the ability of photon counting detectors. This modality, therefore, has the ability to quantify bone mineral density and may be an alternative to dual-energy X-ray absorptiometry (DEXA) scan in the routine clinical screening of high-risk individuals for osteoporosis.  PCD-CT Spectral Topogram may, therefore, be an opportunistic way to increase osteoporosis screening for individuals undergoing CT, particularly at-risk populations.

The purpose of this study is to assess the connection between patients with bone metabolism issues and fragility fractures, identifying risk factors for fragility fractures including vitamin D deficient populations.

The purpose of this study is to determine if denosumab prior to parathyroid scan in patients with recurrent or persistent primary hyperparathyroidism and osteoporosis or osteopenia improves localization of parathyroid adenomas.

The purpose of this study is to determine prevalence and incidence of osteopenia, osteoporosis, and fractures in patients with adenomas based on hormonal sub-type, and to determine the effect of abnormal steroid metabolome on bone density, bone metabolism, and fractures.