Shigao Chen, Ph.D.

The purpose of this study is to evaluate the effectiveess of a new 3D ultrasound imaging technology combining B-mode, microvessel imaging, shear wave elastography, and machine learning for breast lesion diagnosis.

The overall goal of this project is to study a new 3D ultrasound imaging technology for evaluation of axillary lymph nodes in patients with breast cancer.

The purpose of this study is to investigate the value of ultrasound microvessel imaging for evaluation of transplant kidney health.

The purpose of this study is to investigate the effectiveness of ultrasound imaging for staging liver steatosis, using liver fat content measured by MRI as the reference standard.

The purpose of this study is to assess the effectiveness of a new multi-parameter ultrasound technology for evaluation of Crohn’s disease.

The purpose of this study is to test the effectiveness of a new ultrasound microvessel imaging technology for evaluation of chronic kidney disease (CKD).

The purpose of this pilot study is to analyze the effectiveness of a new ultrasound microvessel imaging technology for evaluation of synovitis in patients with rheumatoid arthritis.

The purpose of this study is to find out the optimal acquisition parameters for ultrasound microvessel imaging in healthy volunteers. 

The goal of the project is to develop and test a new 3D Doppler technology, with enhanced vessel sensitivity than conventional Doppler, to employ tumor vascularity as a differential biomarker for improved cancer diagnosis and reduced unnecessary biopsy on benign tumors

The overall goal of this study is to investigate the improvement of sensitivity and penetration of a new contrast enhanced ultrasound (CEUS) technology over those of traditional CEUS.

The purpose of this study is to investigate the use of noninvasive ultrasound shear wave elastography and ultrasound blood vessel imaging to evaluate eosinophilic esophagitis.

The purpose of this study is to assess the effectiveness of a new ultrasound technique for non-invasive evaluation of liver fibrosis.

The purpose of this study is to evaluate an ultrasound technology that may be used to evaluate liver fibrosis.

The purpose of this study is to investigate the value of ultrasound imaging of tumor microvasculature and stiffness as new biomarkers for evaluation of liver tumor.

The overall goal is to investigate the value of ultrasound imaging of small vasculature as a new biomarker for cancer characterization and early treatment evaluation.

The purpose of this study is to investigate the use of shear wave elastography to assess diastolic heart muscle stiffness for diastolic heart failure patients, and compare the stiffness measurements with the cardiac catheterization (cath lab) results.

Liver stiffness measured by MRE can be used for liver fibrosis staging. However, MRE is expensive and not as widely available. The GE Logiq E9 ultrasound scanners in Radiology department can now make shear wave elastography (SWE) measurements. Before these scanners can be used for making clinical measurements for liver fibrosis staging, it is important to evaluate the reliability of SWE measurements on the Logiq E9. The aims of this study are to train sonographers for making SWE measurements,  estimate the variability of the SWE measurements, and estimate the correlation of SWE and MRE measurements.

The purpose of this study is to assess the effectiveness of 2 dimensional shear wave elastography using ultrasound technology, to measure myofascial trigger points and evaluate treatment response.

The purpose of this study is to assess the effectiveness of a new ultrasound technology for evaluating Crohn's disease.

The purpose of this study is to investigate the value of ultrasound imaging of small blood vessels and tumor stiffness as a new biomarker to characterize the disease and evaluate early treatment for cancer.

The purpose of this study is to evaluate the effectiveness of ultrasound reduction imaging for liver steatosis grading using Proton Density Fat Fraction (PDFF) measured by magnetic resonance imaging (MRI) as the reference standard.

The purpose of this study is to try a new ultrasound technology that may be used to measure the tissue stiffness in fibrosis caused by radiation therapy or lymphedema.

The overall goal is to investigate the value of ultrasound imaging of tumor vasculature as a new biomarker for early treatment evaluation.

The overall goal is to investigate the value of ultrasound imaging of small vasculature as a new biomarker for cancer characterization and early treatment evaluation.

The purpose of this study is to investigate the value of ultrasound imaging of microscopic blood vessels as a new biomarker for identifying the difference between benign and cancerous uterine pathologies, and to compare ultrasound imaging to the diagnostics of MRI and (if available), surgical pathology.