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A Prospective, Randomized, Double-Blind, Sham-Controlled, Multi-Center Pivotal Study to Evaluate the Efficacy and Safety of Duodenal Mucosal Resurfacing Using the Revita® System in Subjects with Type 2 Diabetes on Insulin therapy (REVITA-T2Di)
Scottsdale/Phoenix, Ariz.
The purpose of this study is to assess the effectiveness of Revita® DMR for improving HbA1c to ≤ 7% without the need of insulin in subjects with T2D compared to sham and to assess the effectiveness of DMR versus Sham on improvement in Glycemic, Hepatic and Cardiovascular endpoints.
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Confocal Laser Endomicroscopy as an IMaging Biomarker (CLIMB Study) for the Diagnosis of Pancreatic Cystic Lesions
Scottsdale/Phoenix, Ariz.
The purpose of this study is to evaluate EUS-nCLE as an imaging biomarker and PCL fluid DNA analysis as a molecular biomarker for the management of pancreatic cystic lesions (PCLs).
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Mayo Clinic Arizona Endobariatric and Metabolic Therapies Biobank
Scottsdale/Phoenix, Ariz.
Thr purpose of this study is to create a database of clinical information and a repository of biological specimens for genetic, molecular and microbiological research to better understand obesity and changes with treatment to more accurately predict the outcomes of endobariatric and other therapies and to help develop new therapies.
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Outcomes of Comprehensive Treatment of Obesity in Liver Transplant Recipients
Scottsdale/Phoenix, Ariz.
The purpose of this study is to prospectively evaluate the safety and effectiveness of standard of care, individualized, comprehensive weight loss interventions in carefully selected patients with obesity undergoing liver transplant evaluation, including utilization of best lifestyle modifications and guidance to promote a healthy weight, possible medical therapy using FDA-approved weight loss medications and EBMTs with or without concomitant medical therapy.
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Outcomes of Comprehensive Treatment of Obesity in Patients Undergoing Cardiac Transplantation
Scottsdale/Phoenix, Ariz.
The purpose of this study is to prospectively evaluate the safety and effectivenes of standard of care, individualized, comprehensive weight loss interventions in carefully selected patients with obesity undergoing cardiac transplant evaluation, including utilization of best lifestyle modifications and guidance to promote a healthy weight, possible medical therapy using FDA-approved weight loss medications and EBMTs with or without concomitant medical therapy.
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Pilot study of dynamic multiparametric gastric MRI in patients undergoing endoscopic sleeve gastroplasty for the primary treatment of obesity
Scottsdale/Phoenix, Ariz.
The purpose of this study is to assess feasibility of measuring gastric physiologic parameters with dynamic MR imaging pre and postoperatively (3 months) in patients undergoing ESG as primary treatment of obesity
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Quality of Life Assessment in Patients Receiving Cryotherapy for Palliation of Dysphagia in Unresectable Esophageal or Gastroesophageal Junctional Cancer
Scottsdale/Phoenix, Ariz.
The purpose of this study is to determine the effect of endoscopic cryoablation for lessening the effects of dysphagia on the quality of life (QOL) of patients with unresectable esophageal or gastroesophageal junctional cancer.
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EA2185 Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs
Rochester, Minn.,
Jacksonville, Fla.,
Scottsdale/Phoenix, Ariz.
The purpose of this study is to compare the two approaches for monitoring pancreatic cysts - more frequent monitoring vs. less frequent monitoring in order to learn which monitoring method leads to better outcome for patients with pancreatic cysts.
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