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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 221-230 of 3327 for cancer

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  1. Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations

    Scottsdale/Phoenix, AZ, Rochester, MN

  2. OTL38 for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer

    Rochester, MN, Scottsdale/Phoenix, AZ

  3. Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5829 as a Single Agent and In Combination With Enzalutamide in Participants With Metastatic Castrate-Resistant Prostate Cancer

  4. Cancer Prevention: Stories for Change in Hispanic Community

    Rochester, MN

  5. Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. A Study to Compare Docetaxel/Prednisone to Docetaxel/Prednisone Combined with OGX-011 in Men with Prostate Cancer

    Rochester, MN

  7. A Study of Carboplatin, Cabazitaxel and Abiraterone in High Volume Metastatic Castration Sensitive Prostate Cancer (CASCARA)

    Scottsdale/Phoenix, AZ

  8. Study of Cabozantinib Combined With Atezolizumab Vs. Second Novel Hormonal Therapy in Subjects with Metastatic Castration-Resistant Prostate Cancer

    Rochester, MN

  9. A Study of MK-1026 in Patients with Selected Hematologic Malignancies

    Rochester, MN, Scottsdale/Phoenix, AZ

  10. Combination Chemotherapy With or Without Trastuzumab in Treating Women With Breast Cancer

    Eau Claire, WI

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