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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 231-240 of 3327 for cancer

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  1. A Study of PROQOL (Patient Reported Outcome Quality of Life) Tool in the Hematology and Oncology Population

    Rochester, MN

  2. Combination Chemotherapy With or Without Trastuzumab in Treating Women With Breast Cancer

    Eau Claire, WI

  3. Safety and Tolerability of TAR-200 in Subjects With Muscle-Invasive Bladder Cancer Who Are Unfit for Radical Cystectomy

    Scottsdale/Phoenix, AZ

  4. Bicalutamide and Raloxifene Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery

    Scottsdale/Phoenix, AZ

  5. Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. The BEACON Study (Breast Cancer Outcomes With NKTR-102)

  8. Study of XL092 in Combination With Immuno-Oncology Agents in Subjects With Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. Olaparib and Cediranib Maleate in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

    Rochester, MN

  10. Dose Escalation and Expansion Study of GSK525762 in Combination With Fulvestrant in Subjects With Estrogen Receptor Positive (ER+) Breast Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

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