Clinical Trials

The purpose of this study is to develop and pilot test a culturally relevant, Facebook delivered intervention to promote smoking treatment uptake and cessation among Alaska Native (AN) smokers.

Learn more about this study.

The objective of the proposed study is to evaluate the effectiveness and implementation of a culturally adapted, ANAI family-based incentives intervention for smoking cessation.

The goal of this pilot study is to better understand the health of the Somali community in the greater Phoenix area. Healthcare access and clinical service utilization will also be assessed in order to inform future reduction and cessations studies. Social networks will be examined in relation to accessing information about health and tobacco use. Long term objectives related to this study are the development of community-based interventions for tobacco use prevention, reduction, and cessation tailored to reduce disparities related tobacco use among the Somali community.

The primary aim of this study is to retrospectively review the usage, describe the process and assess the outcomes of tobacco cessation e-consultation directed to the Nicotine Dependence Center of the Mayo Clinic (Rochester) from January 2016 to December 2016.

The purpose of this study is to propose a “quit for a bit” intervention to increase measurements of treatment engagement over the postoperative period (defined as the day of surgery to 30 days after surgery), and the willingness to continue treatment after this period, compared to the “quit for good” intervention. 

The purpose of this study is to determine if a brief educational intervention about the connections between smoking and chronic pain will promote the participation in a smoking abstinence therapy program among smokers seeking treatment for chronic pain.

The purpose of this study is to assess the effects of combining varenicline and bupropion SR for a potential additive benefit for helping patients stop smoking for longer periods (≥ 6 months smoking abstinence rates).

The aims of this study are 1) To assess the prevalence of tobacco use and cessation treatment preferences among YKHC employees, 2) To assess employee's current levels of perceived stress, engagement in physical activity, and feelings of resiliency to inform future tobacco cessation interventions, and to examine the relationship between these factors and tobacco use, and 3) To assess YKHC employees' perceptions and opinions of the hospital's current workplace tobacco policy and expansion of these regulations to all YKHC properties.

This present effort is the first step of a larger study. We are limiting the scope this AAIRB application to only the first step. The goal of the overall research study is to examine the acceptability and feasibility of using NMR to inform selection of pharmacologic treatment to increase smoking abstinence among ANAI people.

The aim of this IRB application (Aim 1a) is to refine a metabolism-informed pharmacologic intervention to optimize design and participation of a future pilot.

We will use a community-based participatory research (CBPR) approach with ANAI customer-owners, providers, and leaders to refine ...

This study will evaluate the impact of a proactive, EHR-supported enrollment strategy that links LDCT-eligible smokers with an evidence-based intervention comprised of a web-based program and integrated text messaging. The goal is to provide actionable findings about how to most effectively and cost efficiently promote abstinence in LDCT clinics.

Use of tobacco is very high among Alaska Native women. The investigators are conducting a three phase study. The first phase will examine biomarkers of tobacco exposure in pregnant women and their newborns. The second phase is a qualitative study to translate the biomarker findings into intervention messages. The third phase is a pilot of the biomarker feedback intervention compared with a control condition.

The purpose of this trial is to assess the impact of access to technology and/or coaching support on participation in and response to a behavioral health program for smoking cessation among rural Midwest Mayo Clinic patients.

The purpose of this study is to assess whether regular cigarette smokers who purchase an ENDS product from  Vape Shops that offer personalized coaching on product selection and use can result in regular cigarette smokers completely switching to an ENDS (i.e., discontinue cigarette smoking).

The purpose of this study is to evaluate the feasibility of treating users of E-cigarettes with a 12-week course of varenicline to stop vaping.

This randomized phase III trial studies how well smoking cessation intervention works in reducing surgical complications in patients with newly diagnosed lung cancer who smoke cigarettes. This study will use two smoking cessation interventions: Varenicline (a drug that reduces the craving and withdrawal symptoms that occur with abstinence from nicotine) with behavioral interventions (consisting of a brief clinician-delivered intervention and tobacco quitline [tobacco cessation service available through a toll-free telephone number] follow-up) with placebo (a pill with no active medication) along with the same behavioral interventions. It is not yet known whether smoking cessation intervention prior to surgery is effective ...

This pilot study is being done to adapt an effective 1 session phone coaching intervention for nonsmoking support persons to a low income population. This study will also pilot new intervention components including text messaging and health incentives. The goal of the intervention is for support persons to prompt their smoker to use quitline services. To see if these methods are effective, smokers in this study will be asked to complete assessments about their quit attempts and smoking status. The study will also evaluate if the smokers use quitline services or not. The preliminary findings will be used to provide ...

 Nicotine patches and behavioral therapy may help reduce cigarette smoking and binge drinking in young adults.This randomized clinical trial studies nicotine patches with or without behavioral therapy in reducing cigarette smoking and binge drinking in young adults.

Imbio is developing a Smoking Cessation Report (Report) that includes data analysis from a CT lung cancer screening exam. This randomized controlled (RCT) trial will clinically validate the Report's effectiveness at motivating smokers to call a Quitline.

The purpose of this study is to see whether advice by clinicians to cigarette smokers who are parents of children undergoing elective surgery can reduce the exposure of these children to secondhand smoke in the time around surgery.