Philip A. Araoz, M.D.

Closed for Enrollment

• Cardiac Magnetic Resonance Elastography Rochester, Minn.

  The purpose of this study is to compare myocardial stiffness between subjects with and without heart failure with preserved ejection fraction (HFpEF).

• Cardiac Magnetic Resonance Normal Values Rochester, Minn.

  The purpose of this study is to provide normal reference values for cardiac magnetic resonance elastography.

• Cardiac MRE In Acute Myocardial Infarction Rochester, Minn.

  We have recently developed a new and novel imaging-based technique known as cardiac Magnetic Resonance Elastography (MRE) that is capable of differentiating differing regions of myocardial stiffness in the myocardium.  The condition which myocardial stiffness has been most studied and is thought to vary the most from normal is myocardial infarction. Cardiac MRE findings in acute infarction have not been established and the prognostic significance of cardiac MRE-defined infarct stiffness are unknown. The aims of this study are to compare cardiac MRE stiffness to microvascular obstruction in acute myocardial infarction, to determine the association of cardiac MRE infarct stiffness with left ventricular (LV) remodeling at approximately 6 months follow up, and to determine whether myocardial infarcts show increased stiffness at 6 months follow up.

• Cardiac MRE of Acute Myocardial Infarcts Rochester, Minn.

  The purpose of this study is to determine whether cardiac magnetic resonance elastography (MRE) can detect acute myocardial infarctions in humans as areas of increased stiffness, and to compare cardiac MRE stiffness to microvascular obstruction in acute myocardial infarction.  

• Feasibility of Detecting Changes in Cardiac MRE LV Stiffness in Patients with Hypertrophic Cardiomyopathy and Pre and Post Myectomy Rochester, Minn.

  The purpose of this study is to describe the changes in cardiac Magnetic Resonance Elastography stiffness in Hypertrophic cardiomyopathy patients pre- and post-myectomy.

• Passive Driver Position in Cardiac Magnetic Resonance Elastography (MRE) Rochester, Minn.

  The purpose of this study is to test multiple positions of the passive driver (vibration transmitter) on the patient in Cardiac Magnetic Resonance Elastography (MRE) to find the best position for scanner imaging.

• Pilot Study of Cardiac MRE Myocardial Stiffness in Normal Subjects and Patients with Cardiac Amyloidosis Rochester, Minn.

  The purpose of this study is to use magnetic resonance elastography to assess heart muscle stiffness in patients with cardiac amloidosis compared to normal subjects.

• Pilot Study of Cardiac MRE Myocardial Stiffness in Normal Subjects and Patients with Hypertrophic Cardiomyopathy Rochester, Minn.

  The purpose of this study is to use magnetic resonance elastography to assess heart muscle stiffness in patients with hypertrophic cardiomyopathy compared to normal subjects.