Faculty

Meng Yin, Ph.D.

Clinical Studies

Assessing Renal Health in Patients with Chronic Liver Disease with Multiparametric Hepatorenal MRE/MRI (Hepatorenogram) (Magnetic Resonance Elastography (MRE)) Rochester, Minn.
The purpose of this research is to use advanced 3D kidney MRE imaging for detecting or characterizing hepatorenal syndrome processes, providing capabilities unavailable with other imaging techniques or serum biomarkers.
Noninvasive assessment of portal hypertension and hepatic interstitial pressure with advanced magnetic resonance elastography (MRE) Rochester, Minn.
The purpose of this study is to evaluate the accuracy of 3D vector MRE in predicting hepatic venous pressure gradient (HVPG) and validate its potential to substitute surveillance EGD (“virtual EGD” with risk probabilities output).
Quantitative characterization of the liver-pancreas-adipose axis in diabetes via multiparametric magnetic resonance elastography (MRE) Rochester, Minn.
The purpose of this study is to develop multiparametric magnetic resonance elastography (MRE) imaging protocol to comprehensively characterize tissue microenvironment and microstructure along the liver-pancreas-adipose axis in a longitudinal study of 150 clinical NAFLD patients who had no diabetes (N=50), prediabetes (N=50), and diabetes (N=50). We expect to have 1-year follow-up examinations on at least 120 NAFLD patients assuming a 20% withdraw rate.

Test-Retest Repeatability Study of Free-Breathing Magnetic Resonance Elastography (MRE) of the Liver in Healthy Volunteers and Its Longitudinal Application in Patients with Chronic Liver Diseases Rochester, Minn.
The purpose of this study is to implement a free-breathing hepatic MRE technique capable of being performed in as little as 0.8 seconds per slice which could significantly reduce the breath-hold requirements for typical MRE exams, establish a rapid imaging protocol, and improve clinical patient throughput.